Medium chain fatty acid can someday help in treating heart attacks

Recent study by researchers at the University of MFCC

A heart attack happens when something blocks the blood flood to your heart so it can't get the oxygen it needs." Symptoms include tightness or pain in the chest, neck, back or arms, as well as fatigue, lightheadedness, abnormal heart beat and anxiety. It is also called a myocardial infarction. 

Some heart attack strike suddenly, but many people have warning signs and symptoms hours, days or weeks in advance. 

Heart attacks are still a leading cause of death worldwide, that often come with devastating complications, “said Zhong Wang, Ph.D., an associate professor of cardiac surgery at the University of Michigan Frankel Cardiovascular Center, who is the senior author on a recent preclinical study in Life.”

"Better options are needed to reduce injury to the heart after a heart attack, and even improve heart function. In this publication, we target the interplay between energy and metabolism epigenetics mediated by the medium - chain fatty acid 8C. " 

Wang and colleagues were able to protect against heart attack injury in rat models with octanoic acid, ab eight carbon (8C) medium chain fatty acid, as well as a few other metabolites. Those fatty acids produced acety|-CoA, a building block for energy metabolism, which a stressed heart desperately needs. 

Tha concept is that a physician would administer this therapy to a person once they arrive at the hospital after having a heart attack, to reduce further injury and improve heart function during recovery, he says. 

The Frankel CVC's Department of Cardiac Surgery and the University of Macau in China, who done the study's vital experiments. "Knowledge the crosstalk among vitality metabolic process and epigenetics might not only offer an effective goal for myocardial infarction, but also have broad implications in other ischemic injury - brought about organ damage past cardiac diseases,” said lenglam Lei, Ph.D.

Wang claims the upcoming stage would be to examination this molecule in huge animal’s designs, followed by clinical trials. The recharge team has been studying the epigenetic regulation of heart attack for far more than 10 years.